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cellbind® surface hyperflask® cell culture vessels  (Corning Life Sciences)

 
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    Corning Life Sciences cellbind® surface hyperflask® cell culture vessels
    Immunomodulatory effects and metabolic activities of UC-MSCs manufactured with the Quantum Cell Expansion system and HYPERflasks. (A) Proliferation of CD4 + T cells in the presence of P4-MSCs, QUANT-MSCs, and HYPER/MSCs. Percentage of CD4 + T cell proliferation in the presence of P4-MSCs, HYPER-MSCs, and QUANT-MSCs at PBMC:MSC ratios of 10:1 and 20:1 compared to the control (PBMCs only). (B) Proliferation of CD8 + T cells in the presence of P4-MSCs, QUANT-MSCs, and HYPER/MSCs. Percentage of CD8 + T cell proliferation under the same conditions as in (A). Results demonstrate that both QUANT-MSCs and HYPER-MSCs significantly suppress the proliferation of CD4 + (A) and CD8 + (B) T cells. No significant differences were observed in the suppression of T cell proliferation among P4-MSCs, HYPER-MSCs, and QUANT-MSCs, indicating that both <t>HYPERFlask</t> and Quantum manufacturing methods did not alter the immunoregulatory effects of hUC-MSCs. (C) Glycolysis capacity of P4-MSCs, QUANT-MSCs, and HYPER/MSCs. QUANT-MSCs show reduced glycolysis and glycolytic capacity compared to P4-MSCs and HYPER-MSCs, with no significant differences in basal glycolytic rate or glycolytic reserve among the groups. (D) Mitochondrial respiratory capacity of P4-MSCs, QUANT-MSCs, and HYPER/MSCs including basal respiration rate, proton leakage, maximal respiration, and ATP production, are similar among P4-MSCs, QUANT-MSCs, and HYPER-MSCs. QUANT-MSCs exhibit a higher spare respiratory capacity than input cells (P4-MSCs) and HYPER-MSCs.
    Cellbind® Surface Hyperflask® Cell Culture Vessels, supplied by Corning Life Sciences, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/cellbind+surface+hyperflask+cell+culture+vessel/cellbind++surface+hyperflask++cell+culture+vessels/pmc10205494-281-7-7
    Average 90 stars, based on 1 article reviews
    cellbind® surface hyperflask® cell culture vessels - by Bioz Stars, 2026-09
    90/100 stars

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    1) Product Images from "Advanced cell-based products generated via automated and manual manufacturing platforms under the quality by design principle: Are they equivalent or different?"

    Article Title: Advanced cell-based products generated via automated and manual manufacturing platforms under the quality by design principle: Are they equivalent or different?

    Journal: Heliyon

    doi: 10.1016/j.heliyon.2023.e15946

    Immunomodulatory effects and metabolic activities of UC-MSCs manufactured with the Quantum Cell Expansion system and HYPERflasks. (A) Proliferation of CD4 + T cells in the presence of P4-MSCs, QUANT-MSCs, and HYPER/MSCs. Percentage of CD4 + T cell proliferation in the presence of P4-MSCs, HYPER-MSCs, and QUANT-MSCs at PBMC:MSC ratios of 10:1 and 20:1 compared to the control (PBMCs only). (B) Proliferation of CD8 + T cells in the presence of P4-MSCs, QUANT-MSCs, and HYPER/MSCs. Percentage of CD8 + T cell proliferation under the same conditions as in (A). Results demonstrate that both QUANT-MSCs and HYPER-MSCs significantly suppress the proliferation of CD4 + (A) and CD8 + (B) T cells. No significant differences were observed in the suppression of T cell proliferation among P4-MSCs, HYPER-MSCs, and QUANT-MSCs, indicating that both HYPERFlask and Quantum manufacturing methods did not alter the immunoregulatory effects of hUC-MSCs. (C) Glycolysis capacity of P4-MSCs, QUANT-MSCs, and HYPER/MSCs. QUANT-MSCs show reduced glycolysis and glycolytic capacity compared to P4-MSCs and HYPER-MSCs, with no significant differences in basal glycolytic rate or glycolytic reserve among the groups. (D) Mitochondrial respiratory capacity of P4-MSCs, QUANT-MSCs, and HYPER/MSCs including basal respiration rate, proton leakage, maximal respiration, and ATP production, are similar among P4-MSCs, QUANT-MSCs, and HYPER-MSCs. QUANT-MSCs exhibit a higher spare respiratory capacity than input cells (P4-MSCs) and HYPER-MSCs.
    Figure Legend Snippet: Immunomodulatory effects and metabolic activities of UC-MSCs manufactured with the Quantum Cell Expansion system and HYPERflasks. (A) Proliferation of CD4 + T cells in the presence of P4-MSCs, QUANT-MSCs, and HYPER/MSCs. Percentage of CD4 + T cell proliferation in the presence of P4-MSCs, HYPER-MSCs, and QUANT-MSCs at PBMC:MSC ratios of 10:1 and 20:1 compared to the control (PBMCs only). (B) Proliferation of CD8 + T cells in the presence of P4-MSCs, QUANT-MSCs, and HYPER/MSCs. Percentage of CD8 + T cell proliferation under the same conditions as in (A). Results demonstrate that both QUANT-MSCs and HYPER-MSCs significantly suppress the proliferation of CD4 + (A) and CD8 + (B) T cells. No significant differences were observed in the suppression of T cell proliferation among P4-MSCs, HYPER-MSCs, and QUANT-MSCs, indicating that both HYPERFlask and Quantum manufacturing methods did not alter the immunoregulatory effects of hUC-MSCs. (C) Glycolysis capacity of P4-MSCs, QUANT-MSCs, and HYPER/MSCs. QUANT-MSCs show reduced glycolysis and glycolytic capacity compared to P4-MSCs and HYPER-MSCs, with no significant differences in basal glycolytic rate or glycolytic reserve among the groups. (D) Mitochondrial respiratory capacity of P4-MSCs, QUANT-MSCs, and HYPER/MSCs including basal respiration rate, proton leakage, maximal respiration, and ATP production, are similar among P4-MSCs, QUANT-MSCs, and HYPER-MSCs. QUANT-MSCs exhibit a higher spare respiratory capacity than input cells (P4-MSCs) and HYPER-MSCs.

    Techniques Used: Control

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    Article Snippet: The hepatoma cell lines stably expressing sodium taurocholate cotransporting polypeptide (NTCP), the receptor of hepatitis B virus (HBV) infection, serve as important infection models for studying viral biology and drug discovery.. However, the efficiency of infection greatly varies.. In this study, we studied the effects and potential mechanisms of Matrigel® hESC-qualified (M-hq), a biological basement membrane matrix commonly used in cell culture, on promotion HBV in vitro infection in HepG2-NTCP cells.

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    Immunomodulatory effects and metabolic activities of UC-MSCs manufactured with the Quantum Cell Expansion system and HYPERflasks. (A) Proliferation of CD4 + T cells in the presence of P4-MSCs, QUANT-MSCs, and HYPER/MSCs. Percentage of CD4 + T cell proliferation in the presence of P4-MSCs, HYPER-MSCs, and QUANT-MSCs at PBMC:MSC ratios of 10:1 and 20:1 compared to the control (PBMCs only). (B) Proliferation of CD8 + T cells in the presence of P4-MSCs, QUANT-MSCs, and HYPER/MSCs. Percentage of CD8 + T cell proliferation under the same conditions as in (A). Results demonstrate that both QUANT-MSCs and HYPER-MSCs significantly suppress the proliferation of CD4 + (A) and CD8 + (B) T cells. No significant differences were observed in the suppression of T cell proliferation among P4-MSCs, HYPER-MSCs, and QUANT-MSCs, indicating that both <t>HYPERFlask</t> and Quantum manufacturing methods did not alter the immunoregulatory effects of hUC-MSCs. (C) Glycolysis capacity of P4-MSCs, QUANT-MSCs, and HYPER/MSCs. QUANT-MSCs show reduced glycolysis and glycolytic capacity compared to P4-MSCs and HYPER-MSCs, with no significant differences in basal glycolytic rate or glycolytic reserve among the groups. (D) Mitochondrial respiratory capacity of P4-MSCs, QUANT-MSCs, and HYPER/MSCs including basal respiration rate, proton leakage, maximal respiration, and ATP production, are similar among P4-MSCs, QUANT-MSCs, and HYPER-MSCs. QUANT-MSCs exhibit a higher spare respiratory capacity than input cells (P4-MSCs) and HYPER-MSCs.
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    Immunomodulatory effects and metabolic activities of UC-MSCs manufactured with the Quantum Cell Expansion system and HYPERflasks. (A) Proliferation of CD4 + T cells in the presence of P4-MSCs, QUANT-MSCs, and HYPER/MSCs. Percentage of CD4 + T cell proliferation in the presence of P4-MSCs, HYPER-MSCs, and QUANT-MSCs at PBMC:MSC ratios of 10:1 and 20:1 compared to the control (PBMCs only). (B) Proliferation of CD8 + T cells in the presence of P4-MSCs, QUANT-MSCs, and HYPER/MSCs. Percentage of CD8 + T cell proliferation under the same conditions as in (A). Results demonstrate that both QUANT-MSCs and HYPER-MSCs significantly suppress the proliferation of CD4 + (A) and CD8 + (B) T cells. No significant differences were observed in the suppression of T cell proliferation among P4-MSCs, HYPER-MSCs, and QUANT-MSCs, indicating that both HYPERFlask and Quantum manufacturing methods did not alter the immunoregulatory effects of hUC-MSCs. (C) Glycolysis capacity of P4-MSCs, QUANT-MSCs, and HYPER/MSCs. QUANT-MSCs show reduced glycolysis and glycolytic capacity compared to P4-MSCs and HYPER-MSCs, with no significant differences in basal glycolytic rate or glycolytic reserve among the groups. (D) Mitochondrial respiratory capacity of P4-MSCs, QUANT-MSCs, and HYPER/MSCs including basal respiration rate, proton leakage, maximal respiration, and ATP production, are similar among P4-MSCs, QUANT-MSCs, and HYPER-MSCs. QUANT-MSCs exhibit a higher spare respiratory capacity than input cells (P4-MSCs) and HYPER-MSCs.

    Journal: Heliyon

    Article Title: Advanced cell-based products generated via automated and manual manufacturing platforms under the quality by design principle: Are they equivalent or different?

    doi: 10.1016/j.heliyon.2023.e15946

    Figure Lengend Snippet: Immunomodulatory effects and metabolic activities of UC-MSCs manufactured with the Quantum Cell Expansion system and HYPERflasks. (A) Proliferation of CD4 + T cells in the presence of P4-MSCs, QUANT-MSCs, and HYPER/MSCs. Percentage of CD4 + T cell proliferation in the presence of P4-MSCs, HYPER-MSCs, and QUANT-MSCs at PBMC:MSC ratios of 10:1 and 20:1 compared to the control (PBMCs only). (B) Proliferation of CD8 + T cells in the presence of P4-MSCs, QUANT-MSCs, and HYPER/MSCs. Percentage of CD8 + T cell proliferation under the same conditions as in (A). Results demonstrate that both QUANT-MSCs and HYPER-MSCs significantly suppress the proliferation of CD4 + (A) and CD8 + (B) T cells. No significant differences were observed in the suppression of T cell proliferation among P4-MSCs, HYPER-MSCs, and QUANT-MSCs, indicating that both HYPERFlask and Quantum manufacturing methods did not alter the immunoregulatory effects of hUC-MSCs. (C) Glycolysis capacity of P4-MSCs, QUANT-MSCs, and HYPER/MSCs. QUANT-MSCs show reduced glycolysis and glycolytic capacity compared to P4-MSCs and HYPER-MSCs, with no significant differences in basal glycolytic rate or glycolytic reserve among the groups. (D) Mitochondrial respiratory capacity of P4-MSCs, QUANT-MSCs, and HYPER/MSCs including basal respiration rate, proton leakage, maximal respiration, and ATP production, are similar among P4-MSCs, QUANT-MSCs, and HYPER-MSCs. QUANT-MSCs exhibit a higher spare respiratory capacity than input cells (P4-MSCs) and HYPER-MSCs.

    Article Snippet: The cells were counted and seeded into Corning® CellBIND® Surface HYPERFlask® cell culture vessels at a density of 3400 cells/cm 2 .

    Techniques: Control